Dpph scavenging activity of mallotus oppositifolius. Pdf on jul 1, 2012, fa kabran and others published. Deconstruction of an african folk medicine uncovers a. Evaluation of mallotus oppositifolius methanol leaf extract on the. Mallotus oppositifolius is an open shrub or a tree with elongated branches that can be curved, pendulous or ascending. All structured data from the file and property namespaces is available under the creative commons cc0 license. Article pdf available in biochemistry research international 20. Antidepressant effects of mallotus oppositifolius in acute. This information is available free of charge via the internet at. Antiproliferative and antiplasmodial dimeric phloroglucinols. Epub oct evaluation of mallotus oppositifolius methanol leaf extract on the. Jan 16, 2015 mallotus oppositifolius is a tropical plant used to treat many medical conditions in africa. A third of the global population relies heavily upon traditional or folk medicines, such as the african shrub mallotus oppositifolius. Pdf phytochemical studies and antioxidant properties of.
Pdf antifungal property and phytochemical screening of the crude. Sep 01, 2016 read scientific evidence of plant with a rapidonset and sustained antidepressant effect in a chronic model of depression. Mallotus oppositifolius is used in ghana for cns disorders but very little. Please note that this is a trial program and may end. All the other species are found in east asia, the indian subcontinent, southeast asia, eastern australia, and certain islands of the western pacific.
Antibacterial phloroglucinols derivatives from the leaves. Pdf antidepressant effects of mallotus oppositifolius in. The total antioxidant activity of the mallotus oppositifolius mp extract was estimated by the ferric reducing antioxidant power frap assay and the 1,1diphenyl2picrylhydrazyl dpph photometric assay. Newman osafo, in medicinal plant research in africa, 20. Mallopenins ae, antibacterial phenolic derivatives from the. The methanol leaf extract of mallotus oppositifolius was evaluated for.
Antiinflammatory and antioxidant activities of mallotus. Absolute configurations were assigned by careful comparison of their specific optical rotation. Mallopenins ae, antibacterial phenolic derivatives from. Bluethroated barbet is on bullocks heart fruit annona reticulata. An mallotus oppositifolius in nahilalakip ha genus nga mallotus, ngan familia nga euphorbiaceae. Hydroalcoholic extract of leaves of mallotus oppositifolius moe, a plant used for cns conditions in ghana, was investigated for acute antidepressant effects in the forced swimming. Mallotus oppositifolius is a plant species in the genus mallotus found in africa and madagascar. Mallotus oppositifolius is a shrub that is used traditionally to treat epilepsy, but its potential has not been scientifically validated. Locally it is known as sroti in ewe or strataduca in akan burkill, 1985. Mallotus is a genus of the spurge family euphorbiaceae first described as a genus in 1790. Adsorption and inhibitive action of ethanol extracts of mallotus oppositifolius leaves for the corrosion of mild steel in 1m hydrochloric acid solution.
Mallotus philippensis is a plant in the spurge family. Comparative morphological, anatomical and phytochemical studies on two species of euphorbiaceae m. Structures were elucidated by comprehensive spectroscopic analyses and hrms data. The leaves are taken by hausa in cold infusion for tapeworm 5, 6. Until now, the molecular mechanism was not completely understood. Apr 18, 2015 this page was last edited on 18 april 2015, at 20. However, it must be distinguished from kamala meaning lotus in many indian languages, an unrelated plant, flower, and sometimes metonymic spiritual or artistic concept. Mallotus oppositifolius filed as glinus oppositifolius l. All free radical scavenging assays were carried out in triplicates and the results shown in the figures represent a mean of the values obtained.
Research article evaluation of mallotus oppositifolius. Antiproliferative and antiplasmodial dimeric phloroglucinols from. Mansonia kamerunica asosong mh dec feb forests tree with white flowers, sweet fruits attract bees 16 81. The tropical genus mallotus, a member of the family euphorbiaceae, contains. The antioxidant activity was done in vitro using ferric reducing antioxidant power frap and 1,1diphenyl2hydrazyl dpph spectrophotometric assays. Diabetes which is associated with impaired glucose metabolism leads to oxidative stress which with an attendant protein glycation will produce free radicals 19. The aqueous and ethanol extracts of the plant show antifungal properties, and anti parasitic activity against blastocystis hominis. Callistemenonone a, a novel dearomatic dibenzofurantype. Evaluation of mallotus oppositifolius methanol leaf extract. Mallotus oppositifolius held a place in natural medicine fabricant and farnsworth, 2001. Dmax user guides and product manuals press the sensor number and ent key.
General information kamala is an evergreen tree, growing up to 25 metres tall. The kcnq1 gene belongs to a large family of genes that provide instructions for making potassium channels. The bole is around 10cm in diameter, usually branching from low down. Mallotus oppositifolius, journal of basic and clinical physiology and pharmacology on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. The structures of the new compounds were determined on the basis of spectroscopic evidence, including.
Jun 26, 2019 mallotus oppositifolius can be coppiced and pollarded. The identification of the phytochemicals in the sample was carried out using a qp2010 gas chromatography with thermal desorption system, td 20 coupled with mass spectroscopy. Access is allocated within two business days of purchase and lasts one year. Aug 01, 2019 mallotus oppositifolius mallotus oppositifolius x 3k jpg medias. Mangifera indica anacardiaceae pl, ja arbre fr, me 21 80. Preliminary phytochemical screening conducted on the crude methanol and aqueous extracts of the plant revealed the presence of alkaloids, flavonoids, saponins, tannins, steroids, cardiac glycosides and terpenoids in both extracts of the plant. African journal of biotechnology 2 the rats were fasted overnight before experimentation but were allowed free access to water. Mallotus oppositifolius pdf the methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic. Mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in. Despite the use of mallotus oppositifolius in treating psychiatric and affective disorders in ghana, there is no scientific data on its antidepressant effect. Research article antidepressant effects of mallotus. Deconstruction of an african folk medicine uncovers a novel.
Nwinyi2,5 department of biochemistry, faculty of basic medical sciences, university of calabar, calabar, cross river state, nigeria. At this time of the year you can see numberof butterflies on different flowers and number of birds on flowersfruits. Adongo 2 department of pharmacology, university of ghana medical school, college of health sciences, university of ghana, accra, ghana. Aug 06, 2019 mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in madagascar. Is a shrub that is commonly found in drier types of forest secondary growth throughout the west, african region.
Evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in alloxaninduced diabetic rats. Notes the plants can range from almost completely glabrous to conspicuously hairy. Oct 29, 2019 mallotus oppositifolius filed as glinus oppositifolius l. The herbal medicine, a leaf extract from the shrub mallotus oppositifolius, was previously found to be effective in controlling seizures but the mechanism was unknown. The structures of 15 were confirmed by nmr and mass analyses. Files are available under licenses specified on their description page. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. The antifungal properties of aqueous and ethanol extracts of funtumia elastica and mallotus oppositifolius were carried out using the disc diffusion agar assay.
Mallotus oppositifolius is a tropical plant used to treat many medical conditions in africa. Introduction the cumulative effect of increased free radicals, especially reactive oxygen species ros and reactive nitrogen species rns is the cause of several chronical and degenerative diseases 14. Page 26 26 insert cards all the way in to hear click. Mallotus oppositifolius is widely distributed and occurs from senegal east to ethiopia and south to angola and mozambique, and also in madagascar.
Enter and press button then you will see the osd menu on the monitor. Mallotus oppositifolius mallotus oppositifolius x 3k jpg medias. Pdf evaluation of mallotus oppositifolius methanol leaf extract on. Evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in. Ang mallotus oppositifolius sakop sa kahenera nga mallotus sa kabanay nga euphorbiaceae. The mallotus oppositifolius nyanyafrowais one the oldest. Research article evaluation of mallotus oppositifolius methanol leaf extract on the glycaemia and lipid peroxidation in alloxaninduced diabetic rats. The structures of the new compounds were determined on the basis of spectroscopic evidence, including their 1d. The plant is a common weed of ricefields in bendel state of nigeria 21. A new acylphloroglucinol with a novel architecture including an unprecedented dearomatic dibenzofuran core, named callistemenonone a 1, was isolated from the leaves of callistemon viminalis. In west africa it is grown in and around cassava fields to reduce the impact of animals that feed on the leaves, as they prefer mallotus oppositifolius leaves. Bioassayguided fractionation of an ethanol extract of the leaves and inflorescence of mallotus oppositifolius collected in madagascar led to the isolation of the two new bioactive dimeric phloroglucinols mallotojaponins b 1 and c 2, together with the known mallotophenone 3. A shrub or small tree to m high, common in drier types of forest and in secondary regrowth throughout the region and widespread across tropical africa to madagascar.
The methanol leaf extract of mallotus oppositifolius was evaluated for antiinflammatory activity in rats and mice using acute and chronic antiinflammatory models with acetylsalicylate acid aspirin as the reference drug. Here, we used pharmacological screening and electrophysiological analysis in combination with in silico docking and sitedirected mutagenesis to elucidate the effects of m. Identification and quantification of phytochemical. The antioxidant activity was done in vitro using ferric reducing antioxidant power frap and 1,1diphenyl2hydrazyl.
The procedures were carried out in triplicates and the mean used in computations. Researchers discover molecular mechanisms of an african. Pagka karon wala pay siak nga nalista ubos niini niya. The rats were fasted overnight before experimentation but were allowed free.
Bioassayguided fractionation of an ethanol extract of the leaves and inflorescence of mallotus oppositifolius collected in madagascar led to the isolation of the two new bioactive dimeric phloroglucinols, mallotojaponins b 1 and c 2, together with the known mallotophenone 3. The methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic antiinflammatory. Enhancement of inhibitory neurotransmission and inhibition of. Hydroalcoholic extract of leaves of mallotus oppositifolius moe, a plant used for cns conditions in ghana, was investigated for acute antidepressant effects in the forced swimming fst and tail suspension tests tst. Home archives vol 11 no 2 2018 articles comparative chemotaxonomic studies on sroti mallotus oppositifolius geiseler mull and velvet bush willow mallotus alternifolius merr. Research article antidepressant effects of mallotus oppositifolius in acute murine models kennedyk. Bioactive phloroglucinols from mallotus oppositifolius. Jun 19, 2019 the methanol leaf extract of mallotus oppositifolius was evaluated for anti inflammatory activity in rats and mice using acute and chronic antiinflammatory. Comparative chemotaxonomic studies on sroti mallotus. It has a short, and often fluted bole that can be up to 50cm in diameter, but is usually much less. The chromatographic separation of the components of the acetone extract of mallotus philippensis fruits yielded five new phenolic compounds including two chalcones, 1 and 3, a functionalized phloroglucinol, 2, two flavanones, 4 and 5, and six known compounds.
Treepie is on kumkum tree or kamala tree mallotus philippensis. A maioria sao encontradas no leste e sudeste da asia e, desde a indomalasia ate a nova caledonia e fiji, norte e leste australiano. Gcms analysis for structural identification and bioactive. Thus the present study investigated the effect of the hydroalcoholic leaf extract of the plant in acute antidepressant modelsthe forced swim fst and tail suspension tests tst. Mallotus oppositifolius plant is known locally as kafar mutuwaa by hausas, ija by yorubas andnne okpo kirinya by igbos 5. Beeloving plants for honey food and agriculture organization.
It is known as the kamala tree or red kamala or kumkum tree, due to the fruit covering, which produces a red dye. Pdf phytochemical and biological analysis of mallotus. This article cites 44 articles, 10 of which you can access for free. Evaluation of mallotus oppositifolius methanol leaf. These also show that trevia is embedded within mallotus but. From the ethnomedicinally used leaves of mallotus oppositifolius, four acylphloroglucinol derivatives, namely acronyculatin s u and mallotojaponin d 4 were isolated along with seven known compounds 511. These channels, which transport positively charged atoms ions of potassium out of cells, play key roles in a cells ability to generate and transmit electrical signals. Free fulltext pdf articles from hundreds of disciplines, all in one place. Scientific evidence of plant with a rapidonset and sustained. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in vivo in alloxan diabetic rats as well as its potential antioxidant activity in vitro. Antiinflammatory and antioxidant activities of mallotus oppositifolius. The herbal medicine, a leaf extract from the shrub mallotus oppositifolius, has been used across africa for centuries. Scavenging activity of mallotus oppositifolius a kinetic study. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of the leaves for activities on hyperglycaemia, lipid peroxidation, and increased cholesterol levels in vivo in alloxan diabetic rats as well as its potential antioxidant activity in.
Mallotus e um genero botanico pertencente a familia euphorbiaceae algumas plantas deste genero sao encontrados na africa tropical e madagascar. Mallotus oppositifolius can be coppiced and pollarded. Mallotus comprises about species, which all occur in mzllotus old world tropics, mainly in asia and oceania. An ethanol extract of mallotus oppositifolius geiseler mull. Racemic compounds 1 and 2 were separated by chiralphase hplc, and the. The mallotus oppositifolius nyanyafrowa is one of the oldest tree in the forest but its height and stature remains the same even after a thousand years. Euphorbiaceae is folklorically used to treat diabetic conditions in some parts of nigeria therefore the study, to investigate the extract of.
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